OEM ultrafiltration centrifuge tube manufacturers

Polypropylene centrifuge tubes are known for their strength and resistance to chemicals, making them a popular choice for many applications. However, their hydrophobic nature can lead to increased sample adsorption, which may affect the integrity of the sample. Polyethylene tubes, on the other hand, are more flexible and have better chemical resistance but may not be as durable as polypropylene. Polystyrene tubes offer good clarity and are often used for applications requiring visibility, but they can be more prone to breakage and may not be suitable for all types of samples.

One of the primary challenges with centrifuge tubes is ensuring biocompatibility. This means that the material should not react with the biological samples, causing changes in the sample’s properties or introducing contaminants. For instance, certain materials may leach out chemicals that can interfere with downstream analyses or cause cellular toxicity.

Another challenge is the adsorption of proteins and other biomolecules onto the surface of the centrifuge tube. This can lead to loss of sample material, altered results, and potential cross-contamination between samples. The hydrophobic nature of some materials exacerbates this issue, as they tend to attract and bind proteins more readily.

To address these challenges, researchers and manufacturers have developed various surface modification techniques to improve the biocompatibility and reduce sample adsorption in centrifuge tubes. These techniques can be broadly categorized into physical, chemical, and biological modifications.