Antibody Purification

Antibody Purification

The purified antibodies can then undergo additional processing steps, including concentration, buffer exchange, and sterile filtration, to obtain the final product ready for formulation, characterization, and subsequent use in various applications.

 

Types of Antibody Purification

Chromatography Column

A compact structure and simple operation and maintenance characterize the Hanbon chromatographic column.

 

Chromatography System

Hanbon’s chromatography system offers the Bio-Lab® laboratory chromatography system, the Bio-Pro® pilot&process chromatography system, among other options, and provides dependable performance and customizable design.

 

Buffer Dilution/Conditioning System

It addresses the need for complex buffer solutions to be precise and repeatable, minimizes the number of storage tanks, frees up labor and material resources for dispensing, and lowers the cost of production.

 

Filtration System

Hanbon filtration system is suitable for biopharmaceutical customers with different scales and process routes, including Bio-TFF tangential flow filtration System, Depth filtration system, Membrane cassette holders, etc.

 

Single-use System

We offer single-use tangential flow filtration and chromatography systems, both of which can have their contact liquid components quickly and easily replaced.

 

How is the purity of purified antibodies assessed?

 

The purity of purified antibodies is typically assessed using analytical techniques such as SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis), capillary electrophoresis, size exclusion chromatography, or high-performance liquid chromatography (HPLC). These methods help confirm the absence of impurities and determine the purity and integrity of the antibodies.