High Purity 99.6% Sotagliflozin LX-4211 for heart failure or diabetes CAS NO 1018899-04-1 Pharmaceutical Intermediate

Description of Sotagliflozin LX-4211 from Wuhan Fortuna Chemical Co.,Ltd

Introduction of Sotagliflozin LX-4211.

Sotagliflozin is a medication used to treat adults with type 1 diabetes mellitus. It’s an oral medication that works by inhibiting two proteins involved in glucose regulation: SGLT1 and SGLT2. By inhibiting these proteins, sotagliflozin helps to lower blood sugar levels in people with type 1 diabetes, particularly when used alongside insulin therapy.

 

Application of Sotagliflozin LX-4211.

Sotagliflozin is a medication used to treat type 1 diabetes mellitus. It works by inhibiting two proteins in the body: SGLT1 and SGLT2. By blocking these proteins, sotagliflozin helps to lower blood sugar levels by preventing the absorption of glucose in the intestines and promoting its excretion through the kidneys. This can help people with type 1 diabetes better manage their blood sugar levels in conjunction with insulin therapy.

 

Sotagliflozin mechanism of action.

Sotagliflozin’s mechanism of action involves inhibiting two types of glucose transport proteins: SGLT1 and SGLT2.

1. SGLT2 Inhibition: SGLT2 (Sodium-Glucose Co-transporter 2) is responsible for the reabsorption of glucose from the urine back into the bloodstream in the kidneys. By inhibiting SGLT2, sotagliflozin reduces the reabsorption of glucose, leading to increased urinary excretion of glucose and subsequent lowering of blood glucose levels.

2. SGLT1 Inhibition: SGLT1 (Sodium-Glucose Co-transporter 1) primarily functions in the small intestine, where it is responsible for the absorption of glucose from the diet. By inhibiting SGLT1, sotagliflozin decreases the absorption of glucose from the intestines into the bloodstream, further contributing to the lowering of blood glucose levels.

By inhibiting both SGLT1 and SGLT2, sotagliflozin provides a dual mechanism for reducing blood glucose levels, making it an effective adjunct therapy for individuals with type 1 diabetes mellitus…

 

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